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In addition to these military and political troubles, in 1498 the Portuguese rounded the Cape of Good Hope, establishing a waterway to the East, bypassing the Mediterranean and diverting world trade away from this ancient trade route. But there was one redeeming feature that saved Italy at that time. The rich of Europe forsake gold and silver fabrics for silk and since Italy was one of the few silk manufacturing centers of the continent, this brought a last wave of prosperity to the peninsula, to last about 100 years. Sicily was already growing sugar cane, but in spite of the intervention of Genoese capitalism, the sugar works were money losing ventures. (Ref. 292 )

Central europe

Gold and silver mines flourished again in central Europe from 1470 on for about 70 years. Mining camps were worked by free men in the Alps, the Carpathaians and the Erz Gebirge on the border between Czechoslovakia and Germany. (Ref. 292 )

Germany (see map in section on prussia, in 18th century)

15th century Germany will be described in some detail so that the reader may understand the political and social groundwork on which the Reformation was to burst in full bloom in the next century. The people were the healthiest, strongest, cleanest and most vital and exuberant in Europe. They were actually too vigorous and prosperous to tolerate any longer the manacle of feudalism or the exactions of Rome. The German Church was rich but much of its money continually drained into Rome and a revolutionary spirit of hatred for the Church and the clergy had taken hold of the masses in various parts of the country. In the last half of the century all classes in Germany prospered and with the exception of knights and the lower nobility, although there were sporadic agrarian revolts. The German financiers became prominent, particularly at Augsburg, Bavaria and in particular we must mention the Fuggers family. These and other south German bankers had gained greatly from the mining boom in Germany and Bohemia. (Ref. 279 ) This era of the Fuggers established a center of wealth that Europe had not seen since the millionaires of Imperial Rome. The Fuggers soon moved the center of their operations to Antwerp and this closeness to northern Germany allowed that portion of the country to become divorced from the Italian economy and thus strong enough to protect Luther in the next century. Southern Germany, tied to the Italian economy, remained Catholic. The relative abundance of gold in the last years of the century in Europe paradoxically "launched" the silver mines of Germany. As one of these precious metals becomes more commonplace, the other becomes more valuable. (Ref. 260 ) (See map on page 711)

By 1460 a hundred small cities had won charters of practical freedom from their lay or church superiors. Cologne, with 20,000 people, was the largest town in Germany, functioning as a trade center at the intersection of two Rhine waterways and important overland trade routes. There were still ten times more rural than urban dwellers in the country, although there were about 3,000 towns of all sizes, each acting as a relay point 5 to 8 hours apart on trade routes. (Ref. 260 ) In each principality the three estates - nobles, clergy and commons - met occasionally in a territorial diet that exercised some restraint on the purse strings. Then there was an over-all Reichstag and a Diet of Electors to choose a king, who was then made emperor by the pope. Early in the century, Sigismund of Bohemia (and then also king of Hungary) was the Holy Roman Emperor, but then the Habsburgs of Austria came to power with Albert II in 1438 and after that all the emperors were Habsburgs and thus from outside of Germany, itself . It was not great wonder, then, that Frederick III, in league with the popes, aggravated tension between the popes and the German people and further set the stage for the Reformation. During his reign, the areas of Schleswig-Holstein, Bohemia, Austria and Hungary detached themselves from the German dominion.

Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
What is microbiology
Mercy Reply
studies of microbes
Louisiaste
when we takee the specimen which lumbar,spin,
Ziyad Reply
How bacteria create energy to survive?
Muhamad Reply
Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
_Adnan
But not all bacteria make spores, l mean Eukaryotic cells have Mitochondria which acts as powerhouse for them, since bacteria don't have it, what is the substitution for it?
Muhamad
they make spores
Louisiaste
what is sporadic nd endemic, epidemic
Aminu Reply
the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
explain assimilatory nitrate reduction
Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
what is cell
faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
Akanni
ok
Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
what are emergency diseases
Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
define infection ,prevention and control
Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
Lubega
Heyy Lubega hussein where are u from?
_Adnan
en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
How can Commensal can Bacteria change into pathogen?
Sadik
How can Commensal Bacteria change into pathogen?
Sadik
all
Tesfaye
by fussion
Asiina
what are the advantages of normal Flora to the host
Micheal
what are the ways of control and prevention of nosocomial infection in the hospital
Micheal
what is inflammation
Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
adeolu
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Source:  OpenStax, A comprehensive outline of world history. OpenStax CNX. Nov 30, 2009 Download for free at http://cnx.org/content/col10595/1.3
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