• Card 12 / 17: Using the data in Table 2, calculate the number needed to treat with low?-dose aspirin to prevent 1 ischemic stroke.

    Answer:
    Step 1) Calculate the absolute risk reduction: 221/19,942 . 170/19,934 = 0.0026 or 2.6 fewer cases per 1000 women treated with low?-dose aspirin Step 2)Take the reciprocal of the absolute risk reduction: 1/0.0026=392. Therefore, you would need to treat 392 women with low?-dose aspirin to prevent 1 ischemic stroke.

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Randomized Controlled Trials (RCT), Relative Risk

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Attribution:  Janet, E.A. Forrester, Kwan Ho Kenneth Chui, Steven Cohen, Michael D. Kneeland, Alice Tang, David Tybor. Epidemiology and Biostatistics 2010. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/65/ (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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