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This course is a short series of lectures on Introductory Statistics. Topics covered are listed in the Table of Contents. The notes were prepared by EwaPaszek and Marek Kimmel. The development of this course has been supported by NSF 0203396 grant.

Hypotheses testing - examples.

We have tossed a coin 50 times and we got k = 19 heads . Should we accept/reject the hypothesis that p = 0.5, provided taht the coin is fair?

    Null versus alternative hypothesis:

  • Null hypothesis ( H 0 ) : p = 0.5.
  • Alternative hypothesis ( H 1 ) : p 0.5.

Experiment

Significance level α = Probability of Type I error = Pr[rejecting H 0 | H 0 true]

P [ k < 18 or k > 32 ] < 0.05 .

If k < 18 or k > 32 ] < 0.05 , then under the null hypothesis the observed event falls into rejection region with the probability α < 0.05.

We want α as small as possible.
Test construction.
Cumulative distribution function.
No evidence to reject the null hypothesis.

We have tossed a coin 50 times and we got k = 10 heads . Should we accept/reject the hypothesis that p = 0.5, provided taht the coin is fair?

Experiment

Cumulative distribution function.

P [ k 10 or k 40 ] 0.000025. We could reject hypothesis H 0 at a significance level as low as α = 0.000025.

p -value is the lowest attainable significance level.
In STATISTICS, to prove something = reject the hypothesis that converse is true.

We know that on average mouse tail is 5 cm long. We have a group of 10 mice, and give to each of them a dose of vitamin T everyday, from the birth, for the period of 6 months.

We want to prove that vitamin X makes mouse tail longer. We measure tail lengths of out group and we get the following sample:

Table 1
5.5 5.6 4.3 5.1 5.2 6.1 5.0 5.2 5.8 4.1

  • Hypothesis H 0 - sample = sample from normal distribution with μ = 5 cm.
  • Alternative H 1 - sample = sample from normal distribution with μ >5 cm.

Construction of the test

We do not know population variance, and/or we suspect that vitamin treatment may change the variance - so we use t distribution .

  • X ¯ = 1 N i = 1 N X i ,
  • S = 1 N i = 1 N ( X i X ¯ ) 2 ,
  • t = X ¯ μ S N 1 .

χ 2 test (K. Pearson, 1900)

To test the hypothesis that a given data actually come from a population with the proposed distribution. Data is given in the Table 2 .

Data
0.4319 0.6874 0.5301 0.8774 0.6698 1.1900 0.4360 0.2192 0.5082
0.3564 1.2521 0.7744 0.1954 0.3075 0.6193 0.4527 0.1843 2.2617
0.4048 2.3923 0.7029 0.9500 0.1074 3.3593 0.2112 0.0237 0.0080
0.1897 0.6592 0.5572 1.2336 0.3527 0.9115 0.0326 0.2555 0.7095
0.2360 1.0536 0.6569 0.0552 0.3046 1.2388 0.1402 0.3712 1.6093
1.2595 0.3991 0.3698 0.7944 0.4425 0.6363 2.5008 2.8841 0.9300
3.4827 0.7658 0.3049 1.9015 2.6742 0.3923 0.3974 3.3202 3.2906
1.3283 0.4263 2.2836 0.8007 0.3678 0.2654 0.2938 1.9808 0.6311
0.6535 0.8325 1.4987 0.3137 0.2862 0.2545 0.5899 0.4713 1.6893
0.6375 0.2674 0.0907 1.0383 1.0939 0.1155 1.1676 0.1737 0.0769
1.1692 1.1440 2.4005 2.0369 0.3560 1.3249 0.1358 1.3994 1.4138
0.0046 - - - - - - - -

Are these data sampled from population with exponential p.d.f.?

f ( x ) = e x .

Construction of the test

Are these data sampled from population with exponential p.d.f.?

f ( x ) = a e a x .

  • Estimate a .
  • Use χ 2 test.
  • Remember d.f. = K-2.
Table 1
Actual Situation H o true H o false
decision accept Reject = error t. I reject Accept = error t. II
probability 1 α α = significance level 1 β = power of the test β

Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
What is microbiology
Mercy Reply
studies of microbes
Louisiaste
when we takee the specimen which lumbar,spin,
Ziyad Reply
How bacteria create energy to survive?
Muhamad Reply
Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
_Adnan
But not all bacteria make spores, l mean Eukaryotic cells have Mitochondria which acts as powerhouse for them, since bacteria don't have it, what is the substitution for it?
Muhamad
they make spores
Louisiaste
what is sporadic nd endemic, epidemic
Aminu Reply
the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
explain assimilatory nitrate reduction
Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
what is cell
faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
Akanni
ok
Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
what are emergency diseases
Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
define infection ,prevention and control
Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
Lubega
Heyy Lubega hussein where are u from?
_Adnan
en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
How can Commensal can Bacteria change into pathogen?
Sadik
How can Commensal Bacteria change into pathogen?
Sadik
all
Tesfaye
by fussion
Asiina
what are the advantages of normal Flora to the host
Micheal
what are the ways of control and prevention of nosocomial infection in the hospital
Micheal
what is inflammation
Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
adeolu
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Source:  OpenStax, Collection. OpenStax CNX. Dec 22, 2010 Download for free at http://cnx.org/content/col11259/1.7
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