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In spite of the medical advances small-pox remained widespread and highly virulent, with mortality ranging from 15 to 30%. Throughout this century there were only 9 years in which small-pox deaths in London did not exceed 1,000 and in 1759 they reached 3,296. One-third of the inhabitants of England bore pit marks of that disease. The idea of inoculation by pus from a true small-pox lesion was brought from Turkey by Lady Mary Wortley Montagu and was used for a short time, but was then dropped as too dangerous. It was at the end of the century in 1798 that Edward Jenner published his famous paper on the use of cow-pox for vaccination. Typhus fever occurred sporadically in mild epidemics. Scarlet fever increased in incidence and by 1750 one out of every 30 cases died. A severe epidemic of that occurred in 1777-1778. In spite of all this, life expectancy of 35 years in England was much better than the overall world expectancy of 25 to 30 years. (Ref. 214 , 140 , 125 , 213 )

The War of American Independence was precipitated by the poor policies of ministers such as Grenville and Charles Townshend, but George III's responsibility for the final breach is not to be denied. (Ref. 31 ) Simple in tastes and unpretentious in manner, his mind was still Hanoverian, with an inveterate obstinacy and stubbornness. He could not understand those who feared the consequences of a policy of coercion. Edmund Burke, Secretary to the Marquis of Rockingham, brought the Whig party to stand for conciliation of the colonies as well as relaxation of restraints on the trade of his native Ireland, but the king was not convinced and after 13 months he got rid of Rockingham's government. William Pitt, now ill, went along with the king and Townshend returned to power, with the final result being war. As it progressed the British General Burgoyne's defeat in October of 1777 at Saratoga influenced France, supposedly neutral up until that time, to ally itself with the colonists. The French brought their intact navy up to the line and started a war of revenge against Britain to overcome the sting of the recent Seven Years War. (Ref. 31 ) The revolt of the colonies had shattered England's complacency and the word "reform" was in the air. William Pitt the Younger came to power at age 24 in 1783 and in the next 10 years he tried mightily to stay clear of Europe's upheavals, while he improved the financial, administrative and supply organization of the Royal Navy.

Scotland

The death of the widowed King William left the crowns of both England and Scotland to his sister-in-law Anne. Under some duress by restrictive trade decrees against Scotland, in 1707 a treaty was concluded producing a formal union of the two countries, with a common parliament. But the English continued to harass the Scots.

A Scots proposal to build roads into the Highlands to exploit their great timber resources was rejected by the English, as they continued to import wood from America. English coal could be exported duty free to Ireland, but not to Scotland. Poverty remained endemic but cultivation of the potato on the Stirling plain after 1739 and an increase in the breeding of black cattle began to offer hope for recovery. In the Highlands a warrior society still existed, tribal at the bottom, almost feudal at the top, all using their ancient Gaelic language and existing on the black cattle economy.

Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
What is microbiology
Mercy Reply
studies of microbes
Louisiaste
when we takee the specimen which lumbar,spin,
Ziyad Reply
How bacteria create energy to survive?
Muhamad Reply
Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
_Adnan
But not all bacteria make spores, l mean Eukaryotic cells have Mitochondria which acts as powerhouse for them, since bacteria don't have it, what is the substitution for it?
Muhamad
they make spores
Louisiaste
what is sporadic nd endemic, epidemic
Aminu Reply
the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
explain assimilatory nitrate reduction
Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
what is cell
faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
Akanni
ok
Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
what are emergency diseases
Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
define infection ,prevention and control
Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
Lubega
Heyy Lubega hussein where are u from?
_Adnan
en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
How can Commensal can Bacteria change into pathogen?
Sadik
How can Commensal Bacteria change into pathogen?
Sadik
all
Tesfaye
by fussion
Asiina
what are the advantages of normal Flora to the host
Micheal
what are the ways of control and prevention of nosocomial infection in the hospital
Micheal
what is inflammation
Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
adeolu
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Source:  OpenStax, A comprehensive outline of world history. OpenStax CNX. Nov 30, 2009 Download for free at http://cnx.org/content/col10595/1.3
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