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Learning objectives

By the end of this section, you will be able to:

  • Explain the process by which electric signals are transmitted along a neuron.
  • Explain the effects myelin sheaths have on signal propagation.
  • Explain what the features of an ECG signal indicate.

Nerve conduction

Electric currents in the vastly complex system of billions of nerves in our body allow us to sense the world, control parts of our body, and think. These are representative of the three major functions of nerves. First, nerves carry messages from our sensory organs and others to the central nervous system, consisting of the brain and spinal cord. Second, nerves carry messages from the central nervous system to muscles and other organs. Third, nerves transmit and process signals within the central nervous system. The sheer number of nerve cells and the incredibly greater number of connections between them makes this system the subtle wonder that it is. Nerve conduction is a general term for electrical signals carried by nerve cells. It is one aspect of bioelectricity    , or electrical effects in and created by biological systems.

Nerve cells, properly called neurons , look different from other cells—they have tendrils, some of them many centimeters long, connecting them with other cells. (See [link] .) Signals arrive at the cell body across synapses or through dendrites , stimulating the neuron to generate its own signal, sent along its long axon to other nerve or muscle cells. Signals may arrive from many other locations and be transmitted to yet others, conditioning the synapses by use, giving the system its complexity and its ability to learn.

The figure describes a neuron. The neuron has a cell body with a nucleus at the center represented by a circle. The cell body is surrounded by many thin, branching projections called dendrites, represented by ribbon-like structures. The ends of some of these dendrites are shown connected to the ends of dendrites from another neuron at junctions called synapses. The cell body of the neuron also has a long projection called an axon, represented as a vertical tube reaching downward and ending with thin projections inside a muscle fiber, represented by a tubular structure. The ends of the axon are called nerve endings. The axon is covered with myelin sheaths, each of which is one millimeter in length. The myelin sheaths are separated by gaps, called nodes of Ranvier, each of length zero point zero zero one millimeter.
A neuron with its dendrites and long axon. Signals in the form of electric currents reach the cell body through dendrites and across synapses, stimulating the neuron to generate its own signal sent down the axon. The number of interconnections can be far greater than shown here.

The method by which these electric currents are generated and transmitted is more complex than the simple movement of free charges in a conductor, but it can be understood with principles already discussed in this text. The most important of these are the Coulomb force and diffusion.

[link] illustrates how a voltage (potential difference) is created across the cell membrane of a neuron in its resting state. This thin membrane separates electrically neutral fluids having differing concentrations of ions, the most important varieties being Na + size 12{"Na" rSup { size 8{+{}} } } {} , K + size 12{"K" rSup { size 8{+{}} } } {} , and Cl - size 12{"Cl" rSup { size 8{ +- {}} } } {} (these are sodium, potassium, and chlorine ions with single plus or minus charges as indicated). As discussed in Molecular Transport Phenomena: Diffusion, Osmosis, and Related Processes , free ions will diffuse from a region of high concentration to one of low concentration. But the cell membrane is semipermeable    , meaning that some ions may cross it while others cannot. In its resting state, the cell membrane is permeable to K + size 12{"K" rSup { size 8{+{}} } } {} and Cl - size 12{"Cl" rSup { size 8{ +- {}} } } {} , and impermeable to Na + size 12{"Na" rSup { size 8{+{}} } } {} . Diffusion of K + size 12{"K" rSup { size 8{+{}} } } {} and Cl - size 12{"Cl" rSup { size 8{ +- {}} } } {} thus creates the layers of positive and negative charge on the outside and inside of the membrane. The Coulomb force prevents the ions from diffusing across in their entirety. Once the charge layer has built up, the repulsion of like charges prevents more from moving across, and the attraction of unlike charges prevents more from leaving either side. The result is two layers of charge right on the membrane, with diffusion being balanced by the Coulomb force. A tiny fraction of the charges move across and the fluids remain neutral (other ions are present), while a separation of charge and a voltage have been created across the membrane.

Questions & Answers

What is meant by dielectric charge?
It's Reply
what happens to the size of charge if the dielectric is changed?
Brhanu Reply
omega= omega not +alpha t derivation
Provakar Reply
u have to derivate it respected to time ...and as w is the angular velocity uu will relace it with "thita × time""
do to be peaceful with any body
Brhanu Reply
the angle subtended at the center of sphere of radius r in steradian is equal to 4 pi how?
Saeed Reply
if for diatonic gas Cv =5R/2 then gamma is equal to 7/5 how?
define variable velocity
Ali Reply
displacement in easy way.
Mubashir Reply
binding energy per nucleon
Poonam Reply
why God created humanity
Manuel Reply
Because HE needs someone to dominate the earth (Gen. 1:26)
why god made humenity
Is the object in a conductor or an insulator? Justify your answer. whats the answer to this question? pls need help figure is given above
Jun Reply
ok we can say body is electrically neutral ...conductor this quality is given to most metalls who have free electron in orbital d ...but human doesn't have ...so we re made from insulator or dielectric material ... furthermore, the menirals in our body like k, Fe , cu , zn
when we face electric shock these elements work as a conductor that's why we got this shock
how do i calculate the pressure on the base of a deposit if the deposit is moving with a linear aceleration
ximena Reply
why electromagnetic induction is not used in room heater ?
Gopi Reply
What is position?
Amoah Reply
What is law of gravition
sushil Reply
what is magnetism
Sandeep Reply
Practice Key Terms 4

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