<< Chapter < Page Chapter >> Page >

In addition to the 2 molecules of ATP and NADH the cells gain a series of small intermediates or precursors that are necessary for the construction of monomers which in turn are used to build polymers. These precursors include: Glucose-6-phosphate, Fructose-6-phosphate, Triose-phosphate, 3-Phosphoglycerate, Phosphoenolpyruvate, and Pyruvate . These substrates are the building blocks to form monomers that lead to a variety of biopolymers including including proteins (monomer: amino acids) and polysaccharides.

The net result of glycolysis: 2 pyruvates, 2 NADH and 2 ATP. the other important point is that this is an anaerobic    process. There is no requirement for molecular oxygen in glycolysis. This process occurs in the cytosol or cytoplasm of cells. For a short (3 minute) overview YouTube video of glycolysis click here .

Glycolysis: the oxidation of glucose to pyruvate

Glycolysis is the metabolic process of breaking down or oxidizing hexoses, or six carbon sugars, to two molecules of pyruvate, a three carbon keto acid. The importance of glycolysis is really two fold, first is to generate small carbon compounds that the cell can use as building blocks construct other cellular components. Secondly, many cells, including mammals generate energy in form of ATP from glycolysis. Whhile not all cells generate energy from glycolysis, nearly all living organisms carry out glycolysis as part of their metabolism. The process does not use oxygen and is therefore anaerobic    . Glycolysis takes place in the cytoplasm of bacteral, archeal and eukaryotic cells. Remember that most biological processes are freely reversible, depending upon the needs of the cell. The reverse set of reactions to glycolysis, that is, the process of taking two molecules of pyruvate and reducing them to form one molecule of glucose is called gluconeogenesis . The balance between these two process keeps the flux of carbon (hexoses) sensitive to the needs of the cell.

While glycolysis begins with glucose being activated with the addition of a phosphate from ATP, many different types of hexoses (six carbon sugars) and polysaccharides (polymers of sugars) can feed into glycolysis at the point of glucose or glucose-6-phosphate. Many different hexoses, such as Galactose or Mannose, can be converted to glucose by a hexose isomerase , an enzyme that can rearrange the hydroxyl groups on the hexose and form glucose. Disaccharides (such as lactose, maltose or sucrose), trisaccharides (such as maltose triose) and polysaccharides (longer sugar polymers such as starch or glycogen) can be degraded by hydrolysis reactions to the monomers which can then be converted to glucose and enter glycolysis. The importance of glycolysis and gluconeogenesis, and along with the TCA cycle is central to all cells for the production of compounds necessary to build the monomers for biopolymers. As a result, these pathways has been given the common name of " Central Metabolism ".

Glycolysis begins with the six carbon ring-shaped structure of a single glucose molecule and ends with two molecules of a three-carbon sugar called pyruvate    . Glycolysis consists of two distinct phases. The first part of the glycolysis pathway traps the glucose molecule in the cell and uses energy to modify it so that the six-carbon sugar molecule can be split evenly into the two three-carbon molecules. The second part of glycolysis extracts energy from the molecules and stores it in the form of ATP and NADH, the reduced form of NAD + .

Questions & Answers

how to know photocatalytic properties of tio2 nanoparticles...what to do now
Akash Reply
it is a goid question and i want to know the answer as well
Do somebody tell me a best nano engineering book for beginners?
s. Reply
what is fullerene does it is used to make bukky balls
Devang Reply
are you nano engineer ?
what is the Synthesis, properties,and applications of carbon nano chemistry
Abhijith Reply
Mostly, they use nano carbon for electronics and for materials to be strengthened.
is Bucky paper clear?
so some one know about replacing silicon atom with phosphorous in semiconductors device?
s. Reply
Yeah, it is a pain to say the least. You basically have to heat the substarte up to around 1000 degrees celcius then pass phosphene gas over top of it, which is explosive and toxic by the way, under very low pressure.
Do you know which machine is used to that process?
how to fabricate graphene ink ?
for screen printed electrodes ?
What is lattice structure?
s. Reply
of graphene you mean?
or in general
in general
Graphene has a hexagonal structure
On having this app for quite a bit time, Haven't realised there's a chat room in it.
what is biological synthesis of nanoparticles
Sanket Reply
what's the easiest and fastest way to the synthesize AgNP?
Damian Reply
types of nano material
abeetha Reply
I start with an easy one. carbon nanotubes woven into a long filament like a string
many many of nanotubes
what is the k.e before it land
what is the function of carbon nanotubes?
I'm interested in nanotube
what is nanomaterials​ and their applications of sensors.
Ramkumar Reply
what is nano technology
Sravani Reply
what is system testing?
preparation of nanomaterial
Victor Reply
Yes, Nanotechnology has a very fast field of applications and their is always something new to do with it...
Himanshu Reply
good afternoon madam
what is system testing
what is the application of nanotechnology?
In this morden time nanotechnology used in many field . 1-Electronics-manufacturad IC ,RAM,MRAM,solar panel etc 2-Helth and Medical-Nanomedicine,Drug Dilivery for cancer treatment etc 3- Atomobile -MEMS, Coating on car etc. and may other field for details you can check at Google
anybody can imagine what will be happen after 100 years from now in nano tech world
after 100 year this will be not nanotechnology maybe this technology name will be change . maybe aftet 100 year . we work on electron lable practically about its properties and behaviour by the different instruments
name doesn't matter , whatever it will be change... I'm taking about effect on circumstances of the microscopic world
how hard could it be to apply nanotechnology against viral infections such HIV or Ebola?
silver nanoparticles could handle the job?
not now but maybe in future only AgNP maybe any other nanomaterials
I'm interested in Nanotube
this technology will not going on for the long time , so I'm thinking about femtotechnology 10^-15
can nanotechnology change the direction of the face of the world
Prasenjit Reply
how did you get the value of 2000N.What calculations are needed to arrive at it
Smarajit Reply
Privacy Information Security Software Version 1.1a
Berger describes sociologists as concerned with
Mueller Reply
what does post-translational control refer to?
Teresa Reply
Bioremediation includes
Rachel Reply

Get the best Algebra and trigonometry course in your pocket!

Source:  OpenStax, Ucd bis2a intro to biology v1.2. OpenStax CNX. Sep 22, 2015 Download for free at https://legacy.cnx.org/content/col11890/1.1
Google Play and the Google Play logo are trademarks of Google Inc.

Notification Switch

Would you like to follow the 'Ucd bis2a intro to biology v1.2' conversation and receive update notifications?