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This 33-year-old, insulin-dependent diabetic presented with fever, impaired vision, reddish-black nasal discharge, andconfusion of two days’ duration. He had exophthalmos and external ophthalmoplegia on the right, along with necrosis of the right nasal mucosa andright half of the hard palate. He died 12 hours after admission.
Autopsy demonstrated fungi occluding the right internal carotid artery, severe inflammation of the right orbit, and infarctionof the right cerebral hemisphere.
Mucor organisms typically invade and multiply in arteries and veins, leading to vascular occlusion and tissue necrosis. Thisinfection occurs almost exclusively in immunocompromised patients, especially diabetic patients with ketoacidosis.
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