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- Nitrogen ii
Final exam for all Nitrogen lectures.
| 1. Which of the following statements about the biochemical function of intracellular proteases is
INCORRECT ? |
| A. |
Remove old or misfolded proteins quickly. |
| B. |
Regulate protein activity inside the cells. |
| C. |
Must all work at acidic body pH. |
| D. |
Provide protection against foreign proteins and peptides. |
| E. |
Degrade proteins to sustain nutritional needs in the human body. |
| 2. Which of these is a possible treatment for cystinuria? |
| A. |
Eating a high protein diet with nicotinamide supplements |
| B. |
Eating a low protein diet with arginine therapy |
| C. |
Undergoing gene therapy and taking amino acid conjugation drugs |
| D. |
Drinking at least 6-8 glasses per day of fluids, particularly water |
| E. |
Taking proteasome inhibitors with plenty of fruit juices, soft drinks and coffee |
| 3. A 45-year old sedentary male wants to lose 40 pounds. He decides to try a high protein, low carbohydrate diet. What is the potential risk of consuming too much protein without any physical activity? |
| A. |
Essential amino acids will be missing from his diet. |
| B. |
Develop kidney stones from cystine crystals in urine. |
| C. |
Pancreatitis as a result of accidental trypsin activation. |
| D. |
Damage to lung tissue from activation of elastase. |
| E. |
He will produce excess lipids and glycogen. |
| 4. Which of the following molecules destroys the cell membranes of the hepatic cells causing hyperammonemia? |
| A. |
Carbamoyl Phosphate synthetase I |
| B. |
Excess radicals from alcohol consumption |
| C. |
Ornithine transcarbamoylase |
| D. |
Argininosuccinate synthetase |
| E. |
Argininosuccinate lyase |
| 5. Which of the following digestive enzyme pairs can activate their own zymogens and break proteins into small polypeptides? |
| A. |
Trypsin and pepsin |
| B. |
Aminopeptidase and elastase |
| C. |
Collagenase and chymotrypsin |
| D. |
Carboxypeptidase and dipeptidase |
| E. |
Enterokinase and tripeptidase |
| 6. Which of the following shows the effects of amino acid deficiencies in relation to the carbohydrate metabolic pathways? |
| A. |
Increases the storage of glycogen in both liver and muscle. |
| B. |
Degradation of excess amino acids via the urea cycle. |
| C. |
Stimulates the synthesis of triacylglycerides and VLDL in the liver. |
| D. |
Causes fatigue or exhaustion as a result of decrease levels of ATP. |
| E. |
Increases protein synthesis inside the peripheral tissue cells. |
| 7. Which of the following proteins would be exempt from protein turnover? |
| A. |
Proteins with ubiquitin tails |
| B. |
Proteins with oxidized amino acids |
| C. |
Proteins with PEST sequences |
| D. |
Proteins with specific amino end groups |
| E. |
Proteins in the lenses of the eyes |
| 8. A 4-month old female goes to her well baby check. Physical examination and measurements show a 93% increase in the growth and development scale. In which nitrogen state is this patient right now? |
| A. |
Negative |
| B. |
Positive |
| C. |
Balanced |
| D. |
Intrinsic |
| E. |
Extrinsic |
| 9. Which of the following digestive enzyme pairs can break peptides that are 2-3 amino acids long? |
| A. |
Enterokinase and chymotrypsin |
| B. |
Elastase and collagenase |
| C. |
Carboxypeptidase A and B |
| D. |
Dipeptidase and tripeptidase |
| E. |
Aminopeptidase and Trypsin |
| 10. A 2-year old male has a red, scaly rash that gets worse when the patient is exposed to sunlight. He has short stature, muscle weakness, uncoordinated movements, tremors and involuntary eye movements. He is malnourished and failing to thrive. Blood test results show very low levels of niacin (vitamin B3) and tryptophan. Urine has high levels of amino acids. Stool indoles and urinary indican were elevated after an oral tryptophan loading test was administered. Which of the following disorders is consistent with these lab results? |
| A. |
Atrophic gastritis |
| B. |
Emphysema |
| C. |
Pancreatitis |
| D. |
Cystinuria |
| E. |
Hartnup disease |
Source:
OpenStax, Biochemistry exercises. OpenStax CNX. Apr 06, 2016 Download for free at https://legacy.cnx.org/content/col11386/1.4
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