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a) A micrograph of a spherical cell approximately 4 µm in diameter. B) A micrograph of wavy ribbon shaped cells approximately 10 µm in length. C) a micrograph of a bell shaped cell approximately 50µm in diameter with a tail approximately 200 µm in length. D) An oval shaped cell approximately 100 µm in length. A ring shaped cell approximately 4 µm in diameter; the ring shaped cell is inside a red blood cell.
Eukaryotic cells come in a variety of cell shapes. (a) Spheroid Chromulina alga. (b) Fusiform shaped Trypanosoma . (c) Bell-shaped Vorticella . (d) Ovoid Paramecium . (e) Ring-shaped Plasmodium ovale . (credit a: modification of work by NOAA; credit b, e: modification of work by Centers for Disease Control and Prevention)
  • Identify two differences between eukaryotic and prokaryotic cells.

Nucleus

Unlike prokaryotic cells, in which DNA is loosely contained in the nucleoid region, eukaryotic cells possess a nucleus , which is surrounded by a complex nuclear membrane that houses the DNA genome ( [link] ). By containing the cell’s DNA, the nucleus ultimately controls all activities of the cell and also serves an essential role in reproduction and heredity. Eukaryotic cells typically have their DNA organized into multiple linear chromosomes. The DNA within the nucleus is highly organized and condensed to fit inside the nucleus, which is accomplished by wrapping the DNA around proteins called histones.

A micrograph of a portion of an oval cell. In the center is a darker spherical structure.
Eukaryotic cells have a well-defined nucleus. The nucleus of this mammalian lung cell is the large, dark, oval-shaped structure in the lower half of the image.

Although most eukaryotic cells have only one nucleus, exceptions exist. For example, protozoans of the genus Paramecium typically have two complete nuclei: a small nucleus that is used for reproduction (micronucleus) and a large nucleus that directs cellular metabolism (macronucleus). Additionally, some fungi transiently form cells with two nuclei, called heterokaryotic cells, during sexual reproduction. Cells whose nuclei divide, but whose cytoplasm does not, are called coenocytes .

The nucleus is bound by a complex nuclear membrane , often called the nuclear envelope , that consists of two distinct lipid bilayers that are contiguous with each other ( [link] ). Despite these connections between the inner and outer membranes, each membrane contains unique lipids and proteins on its inner and outer surfaces. The nuclear envelope contains nuclear pores, which are large, rosette-shaped protein complexes that control the movement of materials into and out of the nucleus. The overall shape of the nucleus is determined by the nuclear lamina , a meshwork of intermediate filaments found just inside the nuclear envelope membranes. Outside the nucleus, additional intermediate filaments form a looser mesh and serve to anchor the nucleus in position within the cell.

A micrograph showing an oval cell with a large oval nucleus. The nucleus is red with a bright green outline labeled nuclear lamina. Green lines criss-cross the rest of the cell outside the nucleus.
In this fluorescent microscope image, all the intermediate filaments have been stained with a bright green fluorescent stain. The nuclear lamina is the intense bright green ring around the faint red nuclei.

Nucleolus

The nucleolus is a dense region within the nucleus where ribosomal RNA (rRNA) biosynthesis occurs. In addition, the nucleolus is also the site where assembly of ribosomes begins. Preribosomal complexes are assembled from rRNA and proteins in the nucleolus; they are then transported out to the cytoplasm, where ribosome assembly is completed ( [link] ).

a) A diagram showing the nucleus. A sphere in the center of the nucleus is labeled nucleolus. Lines within the nucleus are labeled chromatin. The fluid of the nucleus is labeled nucleoplasm. The outer region just inside the nuclear envelope is labeled nuclear lamina. The outside of the nucleus is labeled nuclear envelop and pores in the envelope are labeled nuclear pores.  The nuclear envelope is continuous with and becomes the endoplasmic reticulum; a webbing of membranes outside the nucleus. B) A micrograph showing these same structures. The nucleolus is a dark region inside the nucleus which is composed of many lighter lines. The nuclear envelop forms the outside of the nucleus and a pore is seen as a light region in the envelope. Outside the envelope are many lines labeled rough endoplasmic reticulum. A smaller set of lines is labeled mitochondrion overlaying part of the RER.
(a) The nucleolus is the dark, dense area within the nucleus. It is the site of rRNA synthesis and preribosomal assembly. (b) Electron micrograph showing the nucleolus.

Questions & Answers

who is the father of microbiology
kasia Reply
how microbial proteins are used to diagnose infectious diseases
Gift Reply
microbes are cultured on industrial scale and then their secretions are extracted...I think that's called downstream processing
Chaitanya
in which language is the following sentence in omne vivum ex vivo
Chetan Reply
What are the five types of serological tests used to identify microorganism in the laboratory?
Prudence Reply
what is mycobacteria
Taslim Reply
what is gram staining
Nankya Reply
microbiology?
Bekka
It's technique to differentiate bacterial species.The method is discovered by Hans Christian Gram. The bacteria is differentiated as gram positive and gram negative on the basis of peptidoglycan layer which is present in cell wall. The gram positive have peptidoglycan layer.
shamali
What is study of morphology ? and it's classification
Maryam
taxonomy
Kamaluddeen
define the microbes
Saro
word microbes from microns.
Jayeeta
who is the father of microbiology?
Deborah
Antonie van Leeuwenhoek.
shamali
what makes a student to forget what he or she has been taught with easily and how can he or she cope up with it
Samson Reply
to be in touch with subject will help to cope up with the learning life long and also interest matters for subject
shriya
Constant review. And don't worry if you do forget something you always have the option to study it again. Each time you study a certain topic the more it make sense and the more it becomes something natural rather than brute memorization.
Abdi
the cause are many 1.lack of interest . 2. poor attitude to the subject. how can he cope up 1. falling in love with the subject . 2. making it part of you at all times and having determination
Ikilai
understanding the concept and relating whatever course of study with something in his/her day to day activities (i.e in which you are more conversant with in your life).
Kamaluddeen
how many types of cross matching method
umesh
which disease is caused by vicera zoster virus
Timaka Reply
chicken pox
Osuoha
Patients with disseminated herpes zostermay present with severe abdominal pain that results from visceral involvement of varicella-zoster-virus infection. In immunocompetent individuals herpes zoster usually is a localised illness, affecting the skin of one or two adjacent dermatomes.
Kamaluddeen
Actually, it is severe abdominal pain thanks
Osuoha
what causes inflammation of the lung?
Samson
what causes the fungi infection of the vigina
Estar Reply
what causes the fungi infection of the vagina?
Estar
poor hygiene of the area and unprotected sex with infected partner
Kamaluddeen
poor hygiene,some times having sex with infected person or when normal flora enters in the vagina
Ikilai
unprotected sex and poor hygiene are the major but keep in mind that there are some other minor causes also
Samson
what brings about dirt in blood
Sumaiyah Reply
So many factors might be the cause viz. Defects of blood capillaries and certain organs like the liver, the kidneys e.t.c
MOHAMMED
with the above any infection of the body easily enters the bloodstream.
MOHAMMED
there may be fevers which cause septicemia
Ikilai
even taking drug, and eating junk foods .
Ikilai
drinking contaminated water and taking drugs which contains chemical and afterwards they gets absorbed in yo the blood stream
Samson
write a essay about gene library's
anaparthi Reply
Structure of bacteria
Maggy Reply
Outline the classification of viruses according to morphology, nucleic acid, type of diseases, antigenic reaction
chilufya Reply
who is da father of microbiology
Mukomya Reply
Lucie pasture
Felicity
Father of microbiology is Anton von Leuuwenhoek
Anshika
mean Luice pasture the father of microbiology
Felicity
Luice pasture is the father of industrial microbiology
Anshika
who is the father of surgery
Talemwa
father of surgery is Sushruta
Agyekum
sushruta is the father of surgery
Ven.phumie
he Anthony van Lee wen hock
Ikilai
who is the father of medical microbiology
Naveen
he is Anthony van Lee wen hock
Ikilai
Anthony van Lee wen hook
Kamaluddeen
where would we be without microbes
Jessa Reply
nowhere because our body alone also contain billions of microbes.
Edward
in the dreams
Abid
Bangladeshi people's body contain thrice the amount of microbes than regular people.
IamTheMegaExploder
sure?
Kamaluddeen
yah
Kamran
why it was like that
Mمهazn
no where
Mukomya
cocci which are arranged in pairs are called?
umesh
diplococci
vijaya
Cocci are bacterias
Anshika
fimbriae is an organ of ?
umesh
what is the choma like vrius?
PRALHAD
Vibrio cholarea
Kamaluddeen
outline the classification of viruses
chilufya
Fimbriae z an organ of bacteria
Maggy
Antoni van Leeuwenhoek, the father of micro biology
Yang

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Source:  OpenStax, Microbiology. OpenStax CNX. Nov 01, 2016 Download for free at http://cnx.org/content/col12087/1.4
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