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Eosinophils typically represent 2–4 percent of total leukocyte count. They are also 10–12 µ m in diameter. The granules of eosinophils stain best with an acidic stain known as eosin. The nucleus of the eosinophil will typically have two to three lobes and, if stained properly, the granules will have a distinct red to orange color.

The granules of eosinophils include antihistamine molecules, which counteract the activities of histamines, inflammatory chemicals produced by basophils and mast cells. Some eosinophil granules contain molecules toxic to parasitic worms, which can enter the body through the integument, or when an individual consumes raw or undercooked fish or meat. Eosinophils are also capable of phagocytosis and are particularly effective when antibodies bind to the target and form an antigen-antibody complex. High counts of eosinophils are typical of patients experiencing allergies, parasitic worm infestations, and some autoimmune diseases. Low counts may be due to drug toxicity and stress.

Basophils are the least common leukocytes, typically comprising less than one percent of the total leukocyte count. They are slightly smaller than neutrophils and eosinophils at 8–10 µ m in diameter. The granules of basophils stain best with basic (alkaline) stains. Basophils contain large granules that pick up a dark blue stain and are so common they may make it difficult to see the two-lobed nucleus.

In general, basophils intensify the inflammatory response. They share this trait with mast cells. In the past, mast cells were considered to be basophils that left the circulation. However, this appears not to be the case, as the two cell types develop from different lineages.

The granules of basophils release histamines, which contribute to inflammation, and heparin, which opposes blood clotting. High counts of basophils are associated with allergies, parasitic infections, and hypothyroidism. Low counts are associated with pregnancy, stress, and hyperthyroidism.

Agranular leukocytes

Agranular leukocytes contain smaller, less-visible granules in their cytoplasm than do granular leukocytes. The nucleus is simple in shape, sometimes with an indentation but without distinct lobes. There are two major types of agranulocytes: lymphocytes and monocytes (see [link] ).

Lymphocytes are the only formed element of blood that arises from lymphoid stem cells. Although they form initially in the bone marrow, much of their subsequent development and reproduction occurs in the lymphatic tissues. Lymphocytes are the second most common type of leukocyte, accounting for about 20–30 percent of all leukocytes, and are essential for the immune response. The size range of lymphocytes is quite extensive, with some authorities recognizing two size classes and others three. Typically, the large cells are 10–14 µ m and have a smaller nucleus-to-cytoplasm ratio and more granules. The smaller cells are typically 6–9 µ m with a larger volume of nucleus to cytoplasm, creating a “halo” effect. A few cells may fall outside these ranges, at 14–17 µ m. This finding has led to the three size range classification.

Questions & Answers

what is the difference between anatomy and physiology
MICHAEL Reply
Anatomy means structures and physiology means functions
Aliyu
brain behaviour relation
Sneha Reply
Act as mother of all gland
johnson
What is neurons?
Luqman Reply
a specialized cell transmitting nerve impulses; a nerve cell.
Shain
😊
Luqman
thanks
Luqman
why are cells small
Hajiahamdy Reply
what is the change if take normal water in our body
Algur Reply
What are variations in physiology
John Reply
pls let's talk about d difference between mitosis and meiosis
olatemiju Reply
through remodeling and formation of new bones
Amoako Reply
please what is it
Monica
what is blood pressure
HALLELUYAH
what is blood pressure reading
HALLELUYAH
sketch and label blood vessels
HALLELUYAH
veins is........
KING
draw the male reproductive system
Jeremaih Reply
hello am new here
Pednyin
how life
Jeremaih
join
Hajiahamdy
Explain how different foods can affect metabolism
Abraham Reply
what is Endocrine system?
Islam Reply
which secrete hormones and other products direct into the blood
Aadi
Cell is basic, structural and functional unit of life
Kabuja Reply
The cell is the structural and functional unit of all living organisms, and is sometimes called the "building block of life." Some organisms, such as bacteria, are unicellular, consisting of a single cell.
Br_
hi am new here..wish to join you in this conversation
Rachel
welcome Rachel am Brianito
hingi
hey
HALLELUYAH
can some one help
HALLELUYAH
what is the basic function of the lymphatic system
HALLELUYAH
The other main function is that of defense in the immune system. Lymph is very similar to blood plasma: it contains lymphocytes. It also contains waste products and cellular debris together with bacteria and proteins. Associated organs composed of lymphoid tissue are the sites of lymphocyte producti
Adnan
the function of lymphatic system are 1fluid balance 2 lipid absorption and 3 defence
Sidra
destroyed microognism
Usman
lymphatic systems main function is to transport lymph
Colleen
may i know the meaning of infestation of parasite?
Aminiely
Which of the following accurately describe external respirations
Robin Reply
different between anatomy and physiology
Samwel Reply
anatomy is the study of STRUCTURE of the body while physiology is the study of the function of the part of the body
Gborgbor
Anatomy deals with the structure and parts of the body while physiology is the function of the the body parts
Archie
Anatomy is the study which deals with anatomical position while physiology deals with the function
Luqman
not understanding what is a cell
Kesa Reply
its the fundamental unit of life or its the primary step in which two or more cell combine to form a tissue .
Sidra
Is the smallest structural and functional unit of life
Aliyu
cell is the basic you unit of life
Esther

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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