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The source of those differences lay in England’s domestic problems. Increasingly in the early 1600s, the English state church—the Church of England, established in the 1530s—demanded conformity, or compliance with its practices, but Puritans pushed for greater reforms. By the 1620s, the Church of England began to see leading Puritan ministers and their followers as outlaws, a national security threat because of their opposition to its power. As the noose of conformity tightened around them, many Puritans decided to remove to New England. By 1640, New England had a population of twenty-five thousand. Meanwhile, many loyal members of the Church of England, who ridiculed and mocked Puritans both at home and in New England, flocked to Virginia for economic opportunity.

The troubles in England escalated in the 1640s when civil war broke out, pitting Royalist supporters of King Charles I and the Church of England against Parliamentarians, the Puritan reformers and their supporters in Parliament. In 1649, the Parliamentarians gained the upper hand and, in an unprecedented move, executed Charles I. In the 1650s, therefore, England became a republic, a state without a king. English colonists in America closely followed these events. Indeed, many Puritans left New England and returned home to take part in the struggle against the king and the national church. Other English men and women in the Chesapeake colonies and elsewhere in the English Atlantic World looked on in horror at the mayhem the Parliamentarians, led by the Puritan insurgents, appeared to unleash in England. The turmoil in England made the administration and imperial oversight of the Chesapeake and New England colonies difficult, and the two regions developed divergent cultures.

The chesapeake colonies: virginia and maryland

The Chesapeake colonies of Virginia and Maryland served a vital purpose in the developing seventeenth-century English empire by providing tobacco, a cash crop. However, the early history of Jamestown did not suggest the English outpost would survive. From the outset, its settlers struggled both with each other and with the native inhabitants, the powerful Powhatan, who controlled the area. Jealousies and infighting among the English destabilized the colony. One member, John Smith, whose famous map begins this chapter, took control and exercised near-dictatorial powers, which furthered aggravated the squabbling. The settlers’ inability to grow their own food compounded this unstable situation. They were essentially employees of the Virginia Company of London, an English joint-stock company, in which investors provided the capital and assumed the risk in order to reap the profit, and they had to make a profit for their shareholders as well as for themselves. Most initially devoted themselves to finding gold and silver instead of finding ways to grow their own food.

Early struggles and the development of the tobacco economy

Poor health, lack of food, and fighting with native peoples took the lives of many of the original Jamestown settlers. The winter of 1609–1610, which became known as “the starving time,” came close to annihilating the colony. By June 1610, the few remaining settlers had decided to abandon the area; only the last-minute arrival of a supply ship from England prevented another failed colonization effort. The supply ship brought new settlers, but only twelve hundred of the seventy-five hundred who came to Virginia between 1607 and 1624 survived.

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In biology, a pathogen (Greek: πάθος pathos "suffering", "passion" and -γενής -genēs "producer of") in the oldest and broadest sense, is anything that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term pathogen came into use in the 1880s.[1][2
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Source:  OpenStax, U.s. history. OpenStax CNX. Jan 12, 2015 Download for free at http://legacy.cnx.org/content/col11740/1.3
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