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Lysosomes

In animal cells, the lysosomes are the cell’s “garbage disposal.” Digestive enzymes within the lysosomes aid the breakdown of proteins, polysaccharides, lipids, nucleic acids, and even worn-out organelles. In single-celled eukaryotes, lysosomes are important for digestion of the food they ingest and the recycling of organelles. These enzymes are active at a much lower pH (more acidic) than those located in the cytoplasm. Many reactions that take place in the cytoplasm could not occur at a low pH, thus the advantage of compartmentalizing the eukaryotic cell into organelles is apparent.

Lysosomes also use their hydrolytic enzymes to destroy disease-causing organisms that might enter the cell. A good example of this occurs in a group of white blood cells called macrophages, which are part of your body’s immune system. In a process known as phagocytosis, a section of the plasma membrane of the macrophage invaginates (folds in) and engulfs a pathogen. The invaginated section, with the pathogen inside, then pinches itself off from the plasma membrane and becomes a vesicle. The vesicle fuses with a lysosome. The lysosome’s hydrolytic enzymes then destroy the pathogen ( [link] ).

In this illustration, a eukaryotic cell is shown consuming a bacterium. As the bacterium is consumed, it is encapsulated into a vesicle. The vesicle fuses with a lysosome, and proteins inside the lysosome digest the bacterium.
A macrophage has phagocytized a potentially pathogenic bacterium into a vesicle, which then fuses with a lysosome within the cell so that the pathogen can be destroyed. Other organelles are present in the cell, but for simplicity, are not shown.

Vesicles

Vesicles are membrane-bound sacs that function in storage and transport. Vesicles can fuse with other membranes within the cell system.

Art connection

This figure shows the nucleus, rough ER, Golgi apparatus, vesicles, and plasma membrane. The right side of the rough ER is shown with an integral membrane protein embedded in it. The part of the protein facing the inside of the ER has a carbohydrate attached to it. The protein is shown leaving the ER in a vesicle that fuses with the cis face of the Golgi apparatus. The Golgi apparatus consists of several layers of membranes, called cisternae. As the protein passes through the cisternae, it is further modified by the addition of more carbohydrates. Eventually, it leaves the trans face of the Golgi in a vesicle. The vesicle fuses with the cell membrane so that the carbohydrate that was on the inside of the vesicle faces the outside of the membrane. At the same time, the contents of the vesicle are released from the cell.
The endomembrane system works to modify, package, and transport lipids and proteins. (credit: modification of work by Magnus Manske)

Ribosomes

Ribosomes are the cellular structures responsible for protein synthesis. When viewed through an electron microscope, free ribosomes appear as either clusters or single tiny dots floating freely in the cytoplasm. Ribosomes may be attached to either the cytoplasmic side of the plasma membrane or the cytoplasmic side of the endoplasmic reticulum. Electron microscopy has shown that ribosomes consist of large and small subunits. Ribosomes are enzyme complexes that are responsible for protein synthesis.

Because protein synthesis is essential for all cells, ribosomes are found in practically every cell, although they are smaller in prokaryotic cells. They are particularly abundant in immature red blood cells for the synthesis of hemoglobin, which functions in the transport of oxygen throughout the body.

Mitochondria

Mitochondria (singular = mitochondrion) are often called the “powerhouses” or “energy factories” of a cell because they are responsible for making adenosine triphosphate (ATP), the cell’s main energy-carrying molecule. The formation of ATP from the breakdown of glucose is known as cellular respiration. Mitochondria are oval-shaped, double-membrane organelles ( [link] ) that have their own ribosomes and DNA. Each membrane is a phospholipid bilayer embedded with proteins. The inner layer has folds called cristae, which increase the surface area of the inner membrane. The area surrounded by the folds is called the mitochondrial matrix. The cristae and the matrix have different roles in cellular respiration.

In keeping with our theme of form following function, it is important to point out that muscle cells have a very high concentration of mitochondria because muscle cells need a lot of energy to contract.

This transmission electron micrograph of a mitochondrion shows an oval, outer membrane and an inner membrane with many folds called cristae. Inside of the inner membrane is a space called the mitochondrial matrix.
This transmission electron micrograph shows a mitochondrion as viewed with an electron microscope. Notice the inner and outer membranes, the cristae, and the mitochondrial matrix. (credit: modification of work by Matthew Britton; scale-bar data from Matt Russell)

Section summary

Like a prokaryotic cell, a eukaryotic cell has a plasma membrane, cytoplasm, and ribosomes, but a eukaryotic cell is typically larger than a prokaryotic cell, has a true nucleus (meaning its DNA is surrounded by a membrane), and has other membrane-bound organelles that allow for compartmentalization of functions. The plasma membrane is a phospholipid bilayer embedded with proteins. The nucleolus within the nucleus is the site for ribosome assembly. Ribosomes are found in the cytoplasm or are attached to the cytoplasmic side of the plasma membrane or endoplasmic reticulum. They perform protein synthesis. Mitochondria perform cellular respiration and produce ATP. Vesicles are storage and transport compartments.

The endomembrane system includes the nuclear envelope, the endoplasmic reticulum, Golgi apparatus, lysosomes, vesicles, as well as the plasma membrane. These cellular components work together to modify, package, tag, and transport membrane lipids and proteins.

Art connections

[link] Why does the cis face of the Golgi not face the plasma membrane?

[link] Because that face receives chemicals from the ER, which is toward the center of the cell.

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Questions & Answers

In the digestive system,what are nucleotides and what is their use
Leo Reply
what is the difference between kidney and liver
Raphael
what's an isomer
marybertiny Reply
is a chemical species with the same number and types of atoms as another chemical species but with distinct properties because rhe atoms are arranged into different chemical structures.
yaad
How are they important to anmals
Leo
immune system protect body from harmful foreign cells
Hira Reply
that's right some time when bacteria attached the body the immune system product
abdala
what is function of the body
Sarat Reply
Body funtion. Our bodies consist of a number of biological systems that carry out specific functions necessary for everyday living. The job of the circulatory system is to move blood, nutrients, oxygen, carbon dioxide, and hormones, around the body. It consists of the heart, blood, blood vessels,art
Sayed
what's the function of the lymphatic system
Samuel
how long does it take for food process to reach the deudenum
Braveson
how does it takes for food to digested
Kelliann
how long does it takes for food to digested
Kelliann
what are tissue
Nkeng Reply
what are the difference type of connective tissue
Nkeng
Types of connective tissue 1. Loose connective tissue: a.Areolar connective tissue b.Adipose connective tissue 2. Dense (fibrous) connective tissue: I. Compact tissue a.White fibrous tissue ( tendon and sheath) b.Yellow elastic tissue (Ligament) II. Supporting connective tissue: types- 1. Cartilag
iti
2. Bone III. Fluid or liquid connective tissue: Blood lymph
iti
What is cytoplasm
Uyi Reply
what is cytoplasm
Morgan
a cytoplasm is a fluid found inside the cell membrane which contains dissolved minerals e.t.c.
Fortune
ok
Morgan
why is the the mitochondria known as the power house?
Fortune
The mitochondria is involved in releasing energy from food..this process is known as cellular respiration.
Sherice
ok
Fortune
what is Deoxyribonucleic Acid (DNA)?
Jackson
is a molecule composed of two chains.
Fortune
is a molecule composed of two chains that coil around each other to form a double helix carrying the genetics instructions used in growth,development e.t.c.
Fortune
Thanks
Jackson
structur of the heart
Munyah Reply
hi
Unimke
Hello
Mariam
miss Mariam u are welcome
Emmanuel
hello
wana
hii
Dein-aboh
hi
Wani
how
Renzo
hello every one
BOBO
hello
iti
hello
Hilmi
hello
Eshiemoghie
hi
Vaishnavi
what is mutation?
Oliver
Hi to everybody
Hussein
essay for photosynthesis
NiCho Reply
essay of the human body
NiCho
how do female menstrual uterus prepare for fertilisation?
Jackson
what is blood pressure
Sid Reply
to my understanding blood pressure is where u are shock with something emergency I think that can also course blood pressure
Badu
what is the meaning of extended family
Shellyann Reply
extended family is two are more nuclear family living together under one roof
Nordalee
what is genetic engineering
Ebot Reply
good day please what is a cell?
Colota Reply
cell is the basic unit of all living things/organism
Hassan
differenciate b/w cilia and flagellum
Abshira
Cilia: 1. They are smaller in number. 2. Cilia usually occur throughout or major part of the surface of a cell. 3. They beat oar like and in a co-ordinated rhythm 4. Cilia help in locomotion, feeding, circulation, etc.. 5. Example: Paramecium
iti
Flagella: 1. They are larger in size. ADVERTISEMENTS: 2. Flagella are commonly found at one end of the cell. 3. The flagella beat whip-like and independently. 4. Flagella help in locomotion. 5. Example: Euglena
iti
smallest structural and functional unit of an organism!
zidane
cell is the basic unit of all living things
Lukman
A cell is a basic unit of life
Badu
please I want to know the meaning of Tissues
Badu
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Ebot
h2
Oliver
meaning of dispesing
Oliver
thnk u iti
Abshira
tissue is a group of identical cells having common origin
iti
what is the word? dispensing or dispersing...check the spelling of the word.
iti
dispersing
Oliver
Smaller in size not in number
Md
They are small in size and more in number
Md
Not identical but similar
Md
 cell is the smallest unit of life. Cellsare often called the "building blocks of life". The study of cells is called cellbiology. Cells consist of cytoplasm enclosed within a membrane, which contains many biomolecules such as proteins and nucleic acids.
Harun
hi
Vaishnavi
how are u doing
Emmanuel
this thing I don't know whether is an instruments use to measure pressure Sphygmomanometer is it true or not because in my formal school that's my master told me
Badu
dispersing means distribution or spreading
iti
sphygmomanometer is used for measuring blood pressure
iti
thanks
Oliver
mention the functions of mitochondria?
Oliver
mitochondria is the powerhouse of cell. it generates and stores energy in the form of ATP molecules in its oxysomes. it has its own DNA so its capable of self replicating and hence also called as semi autonomous organelle
iti
welcome
iti
explain briefly anatomy
Oliver
anatomy is thr study of internal structures and their organization as well as functions of living organisms
iti
OK thanky
Oliver
Yes
Hilmi
Good
Moses
welcome
iti
differenciate b/w red blood cell and whight blood cell
BOBO
d
Wani
what is homeostasis
alex Reply
the ability of an organism to maintain stable internal environment, even when the external environment changes
Bee
what's the function of the hypothalamus
Agyekum
The hypothalamus is apart of the lower middle brain that tells the pituitary glands when to release hormones
taehyunggg
what is homeostasis
Edward Reply
constant maintenance of internal body temperature
Agyekum
What is the function of the Pituitary Gland?
WeNdlovu
how can homeostasis be maintained?
alex
pituitary gland also known as the master gland secretes hormones which triggers other gland to secretes their hormones
Agyekum
what's the full meaning of DNA and RNA
Deborah Reply
DNA is Deoxyribonucleic acid and RNA means Ribonucleic acid
Christian

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Source:  OpenStax, Human biology. OpenStax CNX. Dec 01, 2015 Download for free at http://legacy.cnx.org/content/col11903/1.3
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