<< Chapter < Page Chapter >> Page >
By the end of this section, you will be able to:
  • Explain how ATP is used by the cell as an energy source
  • Describe the overall result in terms of molecules produced of the breakdown of glucose by glycolysis

Even exergonic, energy-releasing reactions require a small amount of activation energy to proceed. However, consider endergonic reactions, which require much more energy input because their products have more free energy than their reactants. Within the cell, where does energy to power such reactions come from? The answer lies with an energy-supplying molecule called adenosine triphosphate, or ATP    . ATP is a small, relatively simple molecule, but within its bonds contains the potential for a quick burst of energy that can be harnessed to perform cellular work. This molecule can be thought of as the primary energy currency of cells in the same way that money is the currency that people exchange for things they need. ATP is used to power the majority of energy-requiring cellular reactions.

Atp in living systems

A living cell cannot store significant amounts of free energy. Excess free energy would result in an increase of heat in the cell, which would denature enzymes and other proteins, and thus destroy the cell. Rather, a cell must be able to store energy safely and release it for use only as needed. Living cells accomplish this using ATP, which can be used to fill any energy need of the cell. How? It functions as a rechargeable battery.

When ATP is broken down, usually by the removal of its terminal phosphate group, energy is released. This energy is used to do work by the cell, usually by the binding of the released phosphate to another molecule, thus activating it. For example, in the mechanical work of muscle contraction, ATP supplies energy to move the contractile muscle proteins.

Atp structure and function

At the heart of ATP is a molecule of adenosine monophosphate (AMP), which is composed of an adenine molecule bonded to both a ribose molecule and a single phosphate group ( [link] ). Ribose is a five-carbon sugar found in RNA and AMP is one of the nucleotides in RNA. The addition of a second phosphate group to this core molecule results in adenosine di phosphate (ADP); the addition of a third phosphate group forms adenosine tri phosphate (ATP).

This illustration shows the molecular structure of ATP. This molecule is an adenine nucleotide with ribose and a string of three phosphate groups attached to it. The phosphate groups are named alpha, beta, and gamma in order of increasing distance from the ribose sugar to which they are attached.
The structure of ATP shows the basic components of a two-ring adenine, five-carbon ribose, and three phosphate groups.

The addition of a phosphate group to a molecule requires a high amount of energy and results in a high-energy bond. Phosphate groups are negatively charged and thus repel one another when they are arranged in series, as they are in ADP and ATP. This repulsion makes the ADP and ATP molecules inherently unstable. The release of one or two phosphate groups from ATP, a process called hydrolysis, releases energy.

Glycolysis

You have read that nearly all of the energy used by living things comes to them in the bonds of the sugar, glucose. Glycolysis is the first step in the breakdown of glucose to extract energy for cell metabolism. Many living organisms carry out glycolysis as part of their metabolism. Glycolysis takes place in the cytoplasm of most prokaryotic and all eukaryotic cells.

Glycolysis begins with the six-carbon, ring-shaped structure of a single glucose molecule and ends with two molecules of a three-carbon sugar called pyruvate. Glycolysis consists of two distinct phases. In the first part of the glycolysis pathway, energy is used to make adjustments so that the six-carbon sugar molecule can be split evenly into two three-carbon pyruvate molecules. In the second part of glycolysis, ATP and nicotinamide-adenine dinucleotide (NADH) are produced ( [link] ).

If the cell cannot catabolize the pyruvate molecules further, it will harvest only two ATP molecules from one molecule of glucose. For example, mature mammalian red blood cells are only capable of glycolysis, which is their sole source of ATP. If glycolysis is interrupted, these cells would eventually die.

A graphic shows glucose at the top with an arrow pointing down to fructose diphosphate, which then splits into two glyceraldehyde 3-phosphate molecules. Each of these forms one NADH and two ATP molecules in the process of each becoming a pyruvate molecule.
In glycolysis, a glucose molecule is converted into two pyruvate molecules.

Section summary

ATP functions as the energy currency for cells. It allows cells to store energy briefly and transport it within itself to support endergonic chemical reactions. The structure of ATP is that of an RNA nucleotide with three phosphate groups attached. As ATP is used for energy, a phosphate group is detached, and ADP is produced. Energy derived from glucose catabolism is used to recharge ADP into ATP.

Glycolysis is the first pathway used in the breakdown of glucose to extract energy. Because it is used by nearly all organisms on earth, it must have evolved early in the history of life. Glycolysis consists of two parts: The first part prepares the six-carbon ring of glucose for separation into two three-carbon sugars. Energy from ATP is invested into the molecule during this step to energize the separation. The second half of glycolysis extracts ATP and high-energy electrons from hydrogen atoms and attaches them to NAD + . Two ATP molecules are invested in the first half and four ATP molecules are formed during the second half. This produces a net gain of two ATP molecules per molecule of glucose for the cell.

Questions & Answers

what Is taxonom
Don Reply
Taxonom is the the laws and principles guiding the classification of living things either plant 🌿 or animal
Samuel
protein synthesis began with what?
Kesselly Reply
What structures does a plant cell have that an animal cell does not hav
Martin Reply
A plant cell has a cell wall, a large central vacuole, and chloroplasts, which an animal cell does not have.
AI-Robot
what is the function of the cytoskeleton?
Martin
truly. Al-robot
Mark
why is it advantageous for the cell membrane to be fluid in nature?
Martin Reply
The fluid nature of the cell membrane allows for flexibility and dynamic changes in its structure. This allows for the movement of molecules and ions in and out of the cell, as well as the ability to respond to external stimuli. The fluidity of the membrane also allows for the formation of specialized structures such as receptor proteins, which are important for cell-cell communication.
AI-Robot
What is used as a visual marker for successful gene transfer into transgenic animals?
rhonda Reply
Parts of the body involved in homeostasis
Favour Reply
liver
Kirk
A collection of similar-typed cells working together to perform a specific function is called what?
Rachel Reply
tissue
Van
which structure consists of a phospholipid bilayers and it is known as the mosaic model?
Jamar Reply
cell membrane
Abanoub
what is diffusion
Patricia Reply
a passive process of transport
Jamar
Random movement of gas molecule from region of high concentration to a low concentration.
praise
10 difference between male and female reproductive system
Ina Reply
if a phase is omitted ,what will happen to the cell
Ewemoje Reply
discribe advantages and disadvantages of asexual and sexual reproduction
basi Reply
Compared to separate sexes and assuming self-fertilizing is not possible, what might be one advantage and one disadvantage to hermaphroditism?
Gift Reply
is nature of their environment among
basi
cool 😎
Precious
why are the laws of thermodynamics considered laws of nature and not scientific theories
Yolonda Reply
archea were given their own separate domain because they are?
Yolonda
which of the following is a basic component of all of the others?
Yolonda
which of the following organization levels is the least inclusive
Yolonda
which cell feature is absent in bacterial cells
Yolonda
which metric movies the base unit of measurement by one thousandth (0.001)?
Yolonda
What is biology?
Blessing Reply
List the branches of biology
Blessing
List the branches of biology
Blessing
List the branches of biology
Blessing
List the branches of biology
Blessing
Ecology,Anatomy,genetics,biophysics,biochemistry,microbiology and biotechnology.
praise

Get Jobilize Job Search Mobile App in your pocket Now!

Get it on Google Play Download on the App Store Now




Source:  OpenStax, Concepts of biology. OpenStax CNX. Feb 29, 2016 Download for free at http://cnx.org/content/col11487/1.9
Google Play and the Google Play logo are trademarks of Google Inc.

Notification Switch

Would you like to follow the 'Concepts of biology' conversation and receive update notifications?

Ask