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Gas exchange

Gas exchange occurs at two sites in the body: in the lungs, where oxygen is picked up and carbon dioxide is released at the respiratory membrane, and at the tissues, where oxygen is released and carbon dioxide is picked up. External respiration is the exchange of gases with the external environment, and occurs in the alveoli of the lungs. Internal respiration is the exchange of gases with the internal environment, and occurs in the tissues. The actual exchange of gases occurs due to simple diffusion. Energy is not required to move oxygen or carbon dioxide across membranes. Instead, these gases follow pressure gradients that allow them to diffuse. The anatomy of the lung maximizes the diffusion of gases: The respiratory membrane is highly permeable to gases; the respiratory and blood capillary membranes are very thin; and there is a large surface area throughout the lungs.

External respiration

The pulmonary artery carries deoxygenated blood into the lungs from the heart, where it branches and eventually becomes the capillary network composed of pulmonary capillaries. These pulmonary capillaries create the respiratory membrane with the alveoli ( [link] ). As the blood is pumped through this capillary network, gas exchange occurs. Although a small amount of the oxygen is able to dissolve directly into plasma from the alveoli, most of the oxygen is picked up by erythrocytes (red blood cells) and binds to a protein called hemoglobin, a process described later in this chapter. Oxygenated hemoglobin is red, causing the overall appearance of bright red oxygenated blood, which returns to the heart through the pulmonary veins. Carbon dioxide is released in the opposite direction of oxygen, from the blood to the alveoli. Some of the carbon dioxide is returned on hemoglobin, but can also be dissolved in plasma or is present as a converted form, also explained in greater detail later in this chapter.

External respiration occurs as a function of partial pressure differences in oxygen and carbon dioxide between the alveoli and the blood in the pulmonary capillaries.

External respiration

This figure shows the pathway in which external respiration takes place. The exchange of oxygen and carbon dioxide between the alveolus and blood plasma is detailed.
In external respiration, oxygen diffuses across the respiratory membrane from the alveolus to the capillary, whereas carbon dioxide diffuses out of the capillary into the alveolus.

Although the solubility of oxygen in blood is not high, there is a drastic difference in the partial pressure of oxygen in the alveoli versus in the blood of the pulmonary capillaries. This difference is about 64 mm Hg: The partial pressure of oxygen in the alveoli is about 104 mm Hg, whereas its partial pressure in the blood of the capillary is about 40 mm Hg. This large difference in partial pressure creates a very strong pressure gradient that causes oxygen to rapidly cross the respiratory membrane from the alveoli into the blood.

The partial pressure of carbon dioxide is also different between the alveolar air and the blood of the capillary. However, the partial pressure difference is less than that of oxygen, about 5 mm Hg. The partial pressure of carbon dioxide in the blood of the capillary is about 45 mm Hg, whereas its partial pressure in the alveoli is about 40 mm Hg. However, the solubility of carbon dioxide is much greater than that of oxygen—by a factor of about 20—in both blood and alveolar fluids. As a result, the relative concentrations of oxygen and carbon dioxide that diffuse across the respiratory membrane are similar.

Questions & Answers

what's a nervous system
Dante Reply
Is a the group of neurons and glial cells that work together to receive, integrate and responds appropriately to stimulus in the periphery, spinal cord and brain.
study about internal structure, outer structure and their functions
Navdeep Reply
circulatory system on blood pressure
Lakhu Reply
What is ELISA
(enzyme linked immunosorbent assay) is a test that uses antibodies and color change to identify a substance.
what's defense mechanism?
psychological strategies that are unconsciously used to protect a person from anxiety arising from unacceptable thoughts or feelings.
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Binkheir Reply
I believe the apocrine sweat gland uses a sac under the hair follicle and the merocrine sweat gland releases directly on to the surface of the skin
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pankaj Reply
Normal blood volume in adults is 6 litres
4.7 to 5ltr.. normal for adult
what are the advantages of the concave shape of red blood cells?
Amy Reply
This structure is VERY flexible. It can allow these cells to get into the most tiny places in our bodies. a VERY good design! The advantage of red blood cells' biconcave shape is that the surface area is increased to allow more haemoglobin to be stored in the cell.
They can stack so that they can move to capillaries
action of gluteus medius and minimus
Green Reply
Lateral rotation of the hip joint
Briefly explain location of ecg on a patient
Prince Reply
it is a machine that gives a graphical representation of heart beat
Briefly explain location of ecg leads on a patient?
in ecg we use electrical leads over the chest ,ancle and wrist
what is the anatomical and function difference between paravertebral and prevertebral ganglia ?
Rada Reply
types of tissue in human
Preety Reply
charactetistic Of cartilaginous tissue
what is theRecurrent infection?
pankaj Reply
what do you mean about recurrent infection
Recurrent or persistent infection is a manifestation of primary immuno deficiency
weakens the immune system, allowing infections and other health problems to occur more easily
lysis of RBC
What is barometric pressure
Kedha's Reply
what is the agglutination advantage
Gopal Reply
the functions of the liver
Nana Reply
it produces bile juice which is used to make the food smaller
it also plays an important role in conversion of amino acid into urea
it also has role in gluconeogenesis in which amino acids and lipids convert into glucose.
during fetal life it's a center for hemopoiesis (formation of blood cells)
it filters, or removes, harmful substances from the blood
It stores nutrients, such as vitamins and iron,for the body

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