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By the end of this section, you will be able to:
  • Identify four types of organic molecules essential to human functioning
  • Explain the chemistry behind carbon’s affinity for covalently bonding in organic compounds
  • Provide examples of three types of carbohydrates, and identify the primary functions of carbohydrates in the body
  • Discuss four types of lipids important in human functioning
  • Describe the structure of proteins, and discuss their importance to human functioning
  • Identify the building blocks of nucleic acids, and the roles of DNA, RNA, and ATP in human functioning

Organic compounds typically consist of groups of carbon atoms covalently bonded to hydrogen, usually oxygen, and often other elements as well. Created by living things, they are found throughout the world, in soils and seas, commercial products, and every cell of the human body. The four types most important to human structure and function are carbohydrates, lipids, proteins, and nucleotides. Before exploring these compounds, you need to first understand the chemistry of carbon.

The chemistry of carbon

What makes organic compounds ubiquitous is the chemistry of their carbon core. Recall that carbon atoms have four electrons in their valence shell, and that the octet rule dictates that atoms tend to react in such a way as to complete their valence shell with eight electrons. Carbon atoms do not complete their valence shells by donating or accepting four electrons. Instead, they readily share electrons via covalent bonds.

Commonly, carbon atoms share with other carbon atoms, often forming a long carbon chain referred to as a carbon skeleton. When they do share, however, they do not share all their electrons exclusively with each other. Rather, carbon atoms tend to share electrons with a variety of other elements, one of which is always hydrogen. Carbon and hydrogen groupings are called hydrocarbons. If you study the figures of organic compounds in the remainder of this chapter, you will see several with chains of hydrocarbons in one region of the compound.

Many combinations are possible to fill carbon’s four “vacancies.” Carbon may share electrons with oxygen or nitrogen or other atoms in a particular region of an organic compound. Moreover, the atoms to which carbon atoms bond may also be part of a functional group. A functional group    is a group of atoms linked by strong covalent bonds and tending to function in chemical reactions as a single unit. You can think of functional groups as tightly knit “cliques” whose members are unlikely to be parted. Five functional groups are important in human physiology; these are the hydroxyl, carboxyl, amino, methyl and phosphate groups ( [link] ).

Functional Groups Important in Human Physiology
Functional group Structural formula Importance
Hydroxyl —O—H Hydroxyl groups are polar. They are components of all four types of organic compounds discussed in this chapter. They are involved in dehydration synthesis and hydrolysis reactions.
Carboxyl O—C—OH Carboxyl groups are found within fatty acids, amino acids, and many other acids.
Amino —N—H 2 Amino groups are found within amino acids, the building blocks of proteins.
Methyl —C—H 3 Methyl groups are found within amino acids.
Phosphate —P—O 4 2– Phosphate groups are found within phospholipids and nucleotides.

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Source:  OpenStax, Anatomy & Physiology. OpenStax CNX. Feb 04, 2016 Download for free at http://legacy.cnx.org/content/col11496/1.8
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